Creating Tubular Nanofibers with NANON
Nanofiber technology holds great promise for a wide range of applications.In this post, we introduce tubular nanofibers—a unique structure that can be created using our electrospinning device, NANON. What Are Tubular Nanofibers? At our company, we produce straw-like tubular nanofibers by rotating mandrel rods with diameters ranging from 2 mm to 10 mm while spraying a solution jet onto them. These fibers are expected to be applied in a variety of fields, such as medical uses like artificial blood vessels and energy devices. In particular, when using biocompatible polymers, applications in cutting-edge medical fields—such as tissue engineering and drug delivery systems—are expanding. Fabrication of Tubular Nanofibers Using NANON In this demonstration, we created tubular nanofibers using the following setup: Features of Our Tubular Nanofibers ・Uniform Structure The high-speed rotating mandrel collector enables the formation of smooth and consistent nanofibers. ・High Versatility Applicable to a wide range of uses, including filters, biomedical applications, and energy devices. ・Flexible Design The diameter and thickness of the fibers can be controlled by adjusting the size and rotation speed of the collector. Future Outlook As we further advance our tubular nanofiber fabrication technology, we aim to develop materials with even more sophisticated functions. In particular, we anticipate expanded use in the medical field, such as artificial blood vessels and drug delivery systems. Our company continues to enhance our electrospinning technology, striving to provide equipment capable of producing various types of nanofibers. We also actively support researchers and companies by offering equipment customization and tailored operation methods to help≫ more
Development of Nanofiber Membranes with Dual-Threshold Effect to Suppress Zinc Dendrites
Aqueous Zinc-Ion Batteries (AZIBs) have recently gained attention as an eco-friendly, safe, and cost-effective energy storage technology. However, the growth of zinc dendrites and side reactions during repeated charge-discharge cycles remain significant challenges, limiting battery lifespan and efficiency. 🧪 Latest Research Findings A research team led by Professor Yong Liu from Beijing University of Chemical Technology, Professor Ce Wang from Jilin University, and Professor Ping Hu from Tsinghua University published a paper in Advanced Functional Materials titled “Spatial and Electrostatic Dual-Confinement in Hierarchical Hollow Bi-Bi₂O₃@Carbon Nanofibers for Dendrite Suppression and Side Reaction Mitigation in Aqueous Zinc-Ion Batteries.” This study introduces a novel AZIB anode material fabricated using electrospinning, featuring Bi-Bi₂O₃-loaded carbon nanofibers (Bi-Bi₂O₃@CNF) with a hierarchical hollow structure and grooved surface, achieving the following: ✅ Suppression of Zinc Dendrite Growth✅ Reduction of Side Reactions✅ Mitigation of Battery Polarization Figure 1. Fabrication Process of Bi-Bi₂O₃@CNF Composite Material via Electrospinning ⚙️ Structure and Properties of Bi-Bi₂O₃@CNF Composite Material The unique structure and material properties of Bi-Bi₂O₃@CNF create a “Spatial & Electrostatic Dual-Confinement Effect”, enabling uniform zinc deposition on the nanofiber surface and suppressing dendrite formation. Compared to a pure zinc anode, this material demonstrated reduced ohmic resistance, suppressed hydrogen evolution reactions, and alleviated polarization. Figure 2. Electrochemical Performance of Bi-Bi₂O₃@CNF and CNF Half-Cells at Current Densities of 5 mA·cm⁻² and 10 mA·cm⁻² 📊 Electrochemical Performance Comparison Comparative experiments evaluated the performance of Bi-Bi₂O₃@CNF and conventional CNF (carbon nanofibers) under current densities of 5 mA·cm⁻² and 10 mA·cm⁻². The results showed that Bi-Bi₂O₃@CNF≫ more
Addressing Global Water Pollution: Removal of Malachite Green Using ZnO-ZnFe₂O₄ Composite Nanofibers
Water pollution is a global concern, especially synthetic dyes that negatively impact both the environment and human health. This study demonstrates that ZnO-ZnFe₂O₄ composite nanofibers, fabricated via electrospinning using polyvinylpyrrolidone (PVP) as a mediator, effectively remove malachite green (MG), a dye with potential carcinogenic properties, from water. 🔬 Study Overview 💧 Malachite Green Adsorption Performance 📈 Practical Application and Future Outlook This study demonstrates that ZnO-ZnFe₂O₄ nanofibers are effective water treatment materials with high adsorption capacity and reusability, making them promising for industrial wastewater treatment applications. 👉 Read the full study here ＞ ReferencesRaut, S., & Sahoo, S. K. (2024). Removal of malachite green using ZnO-ZnFe₂O₄ nanofibers. Results in Surfaces and Interfaces, 17, 100286. [Online]
【Customer Prototype Example】Double-Sided Coating for Medical Stent Covers
We are pleased to introduce the latest prototype example from one of our customers. Project Theme: Coating stent covers used to expand narrowed arteries. Our electrospinning device utilizes proprietary spray technology, enabling uniform coating on both the inner and outer surfaces of stent covers. This process reduces the risk of the stent material irritating blood vessel tissues, minimizes inflammatory responses, and enhances biocompatibility. With our equipment, coating thickness and uniformity can be precisely controlled, allowing us to deliver products tailored to specific requirements. 🔎 Key Features of Our Device ✅ Dual-Surface Spray Technology: Achieves uniform coating in a short time✅ High-Precision Control: Precisely regulates coating thickness and uniformity✅ Versatile Applications: Compatible with various materials and applications 💡 Benefits for Customers 🔹 Increased Production Efficiency: Reduces coating time and optimizes processes🔹 Cost Reduction: Minimizes material waste and lowers energy consumption🔹 Enhanced Quality: Ensures product performance and reliability If you are interested in this cutting-edge coating technology, please feel free to contact us!
【Paper】A Macrolide-loaded Nanofiber Insert for Sustainable Intraocular Administration Based on Polycaprolactone and Cellulose Acetate: A Pharmacokinetic Study in the Rabbit Eye
➡please click here for the paperA Macrolide-loaded Nanofiber Insert for Sustainable Intraocular Administration Based on Polycaprolactone and Cellulose Acetate: A Pharmacokinetic Study in the Rabbit Eye Bioavailability and DDS Azithromycin (AZM) is a broad-spectrum antibiotic that has anti-inflammatory properties and is used as an ophthalmic agent to treat ocular infections because it acts to cause bacterial conjunctivitis. However, eyedrops have limited bioavailability and require frequent administration. Therefore, in recent years, nano-based novel drug delivery systems that can increase corneal permeation and enhance drug residence lengthening and drug delivery have attracted attention. Bioavailability: an indicator of how well a given drug (formulation) reaches and acts in the systemic circulation. Effectiveness and Prospect of Eye Points by DDS Using Nanofibers Among these methods, the use of nanofibers has characteristics such as high surface area, porous structure, and high drug loading capacity, making it possible to insert nanofibers directly into the conjunctive sac to extend drug residence time at the surface of the conjunctive membrane, and reducing the number of drug dosing, making it one of the most suitable methods for eye-sustaining drug delivery. In practice, a large number of polymers are processed into nanofibers using the electrospinning method. We used cellulose acetate (CA), which is non-toxic, biodegradable, and biocompatible, and polycaprolactone (PCL), a hydrophobic polymer that has received FDA approval for drug delivery, to fabricate nanofibers loaded with AZM and evaluated their efficacy. Since they used to fabricate AZM loaded nanofibers with hydrophilic polymers, they have also evaluated improvements in their pharmaceutical≫ more
Localized cancer photodynamic therapy approach based on core–shell electrospun nanofibers
My name is Tsumugi, and I am a researcher.In this issue, we investigated a localized cancer photodynamic therapy approach based on core-shell electrospun nanofibers! TsumugiShe is a second-year researcher in the Nanofiber Division of MECC.Her hobbies include reading science magazines and the latestresearch papers, as well as karate. Her special skill is speaking Chinese. <Background and Purpose>The fourth largest number of cervical cancers among women. Treatment includes surgery, radiation therapy, and chemotherapy, but side effects are common and efficacy is limited. Therefore, alternative treatments such as photodynamic therapy (PDT) are being considered to minimize side effects and prevent recurrence. PDT is a treatment method based on the principle that various biomolecules are oxidized and the target tissue is irreversibly destroyed by generated singlet oxygen. Photoactive molecules called photosensitizers (PS) are absorbed in the cancerous cells, and PS is activated by irradiating the target site with a specified wavelength. Porphyrins (Por) and their derivatives are commonly used in PS. While Por has advantages such as high singlet oxygen-quantum yield, minimal dark toxicity, and rapid removal from the body, it also has several drawbacks, such as a large amount of dose required for full-body administration to achieve a stable effectiveness, leading to prolonged light sensitivity, and the possibility of compound elimination by targeting the localized area of the tumour. We intend to incorporate PS into the Local Drug Delivery Systems (DDS) to solve these shortcomings. Implantation of a local DDS at or near the tumour site allows direct delivery of PS to≫ more
Ti3C2Tx MXene-embedded MnO2-basedhydrophilic electrospun carbon nanofibers as a freestanding electrode for supercapacitors
Our NANON is used in a study published by Xinyang Normal University in Henan Province, China. This paper focuses on MnO2-based hydrophobic electroplated carbon nanofibers used as self-supporting electrodes. Click here to read the paper ＞＞
MXene-encapsulated hollow Fe3O4 nanochains embedded in N-doped carbon nanofibers with dual electronic pathways as flexible anodes for high-performance Li-ion batteries
The research conducted by Xinyang Normal University in Henan Province, China, utilizes our NANON. This study focuses on developing a new anode material to enhance the performance of lithium-ion batteries by leveraging the high theoretical capacity and environmentally friendly properties of Fe3O4 (iron oxide). Click here to read the paper ＞＞
Hyaluronic Acid Induction Promotes the Differentiation of HumanNeural Crest-like Cells into Periodontal Ligament Stem-like Cells
Dr. Jun Tomoshikiyo et al. of Graduate School of Dentistry, Hokkaido University presented Hyaluronic Acid Induction Promotes the Differentiation of HumanNeural Crest-like Cells into Periodontal Ligament Stem-like Cells Our NANON was used in the paper “Hyaluronic Acid Induction Promotes the Differentiation of HumanNeural Crest-like Cells into Periodontal Ligament Stem-like Cells! The following is a summary of the paper. When the PDL is damaged beyond repair, periodontitis can progress and teeth can be lost. Periodontal tissue contains periodontal tissue stem cells (PDLSCs) that have the ability to regenerate periodontal tissue, but the population of PDLSCs in periodontal tissue is thought to be very small, limiting the transplantation of autologous PDLSCs. Neural crest (NC) cells can differentiate into a variety of cells and tissues, and some NC cells can remain in cranial NCs to give rise to PDLSCs. This suggests that differentiation of NC cells into PDLSCs in periodontal tissues may promote periodontal tissue regeneration. However, the difficulty in obtaining large numbers of NC cells is the main factor limiting the application of NC cells in regeneration research. Therefore, we focused on SK-N-SH cells, a neuroblastoma cell line, as a method to culture periodontal tissue stem cells for periodontal tissue regeneration, and developed a new scaffold for cell culture. I want to take good care of my teeth because I don’t want them to disappear, but it is also difficult to take care of them.If there is a way to regenerate them, it would be very helpful! First, PDL tissue was detached≫ more
Effect of Electrospun Nanofibrous Film on Drilling-Force Reduction for Fine-Hole Drilling in Metals
Our NEX-101 was used in the research presented by Associate Professor Yusuke Date et al. of the Department of Chemistry and Biochemistry, Division of Integrated Engineering, Yonago National College of Technology. We would like to thank them for providing us with their paper. ⇒ Click here to read the paper.